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© 2018 by Tirpack Medical Procedures

WHAT ARE SEX HORMONES AND THEIR FUNCTIONS?

The sex hormones are estrogen, progesterone, and testosterone. Like men, women do produce and NEED testosterone.
Estrogen: the function of estrogen is to make everything grow. It makes the lining of the uterus grow, it makes the breast tissue grow, and it keeps the vagina moisturized.

There are three main types of estrogen that a woman produces:

  • Estradiol (E1)-80% of a woman’s estrogen

  • Estriol (E2)

  • Estrone (E3)

Estradiol is produced directly in the ovaries, estrone is produced from estradiol, and estriol is produced in large amounts during pregnancy. Estradiol is the most potent of the three estrogens.

other functions of estrogen

  • Alleviate symptoms caused by the natural decrease in hormone production in the body

  • Re-establish the individual's hormonal balance

  • Provide protective benefits that were originally provided by the body's naturally occurring hormones.

  • Prevents bone destruction thus prevents osteoporosis.

  • Protects the cardiovascular system reducing blood pressure by relaxing the lining of blood vessels, and preventing plaque buildup.

  • Reduces incidence of diabetes and protects insulin sensitivity through lower insulin levels.

Protects nerve cells and brain function thus helping our memory, improving learning abilities and providing a better quality of sleep.
Works as an antidepressant by increasing serotonin levels.
Progesterone is made in the ovaries after ovulation. Progesterone keeps the estrogen in check by preventing the overgrowth of endometrium, protects against fibrocystic disease.

SYMPTOMS OF ESTROGEN DEFICIENCY

  • hot flashes

  • night sweats

  • vaginal dryness

  • sagging breasts and/or loss of breast fullness

  • mental fogginess

  • depression

  • changes in mood

  • decreased sense of sensuality and sexuality

WHAT IS PROGESTERONE AND THEIR FUNCTION?

  • Oldest known sex hormone

  • Present in every human regardless of age

  • Produced by the ovaries and adrenal gland

  • Secreted by corpus luteum

  • Has receptors in nearly every cell in the body

  • Acts on uterus, kidneys, brain, smooth muscle, breasts, bones, and cellular membranes

  • Metabolized to other active hormones

  • Counteracts estrogen's tendency to induce excess growth in the endometrial lining of the uterus

  • Builds new bone tissue, leading to increased bone mass and density

  • Necessary for maintenance of pregnancy

  • Decreases uterine contractions

  • Prepares and maintains uterine lining for implantation of fertilized egg

  • Prepares breasts for lactation

  • Assists in raising HDL-cholesterol levels (if combined with estrogen therapy) and ultimately reduces risk of heart disease. Synthetic progesterone (progestin) has an overall negative effect on HDL-cholesterol levels because it vasocontricts

WHAT IS PROGESTERONE?

  • What is the difference between "progestin" and "progesterone?"
    The main difference is in the derivative. Progestins are synthetic (i.e. man-made) molecules developed to act like natural progesterone. Natural progesterone is a molecule that is plant derived and is bio-identical to the hormone produced in our bodies. Progestin’s do not have as broad a spectrum of activity as natural progesterone, and have a wide range of side effects. Whereas progesterone may cause some mild to moderate drowsiness, progestins can cause:

  • Breast tenderness

  • Acne

  • Depression

  • Vision changes

  • Bloating

  • Migraine headaches

  • Thrombosis

  • Decreased glucose tolerance

  • Gastric regurgitation

  • Menopause
    A natural part of aging? Yes.

  • However, many people, including doctors would like you believe that you have to live with it. Then as symptoms get worse and your lack of sleep makes you even more of a basket-case, your doctor may write you a prescription for sleeping pills; sleeping pills leading to metabolites that create a "morning after hangover". Or even worse, you may be prescribed medications that further distort your remaining hormone levels. So after having the babies and ensuring the survival of the species you are just suppose to sit back and accept the inevitable.

  • Accept sagging skin

  • Sleepless nights

  • Fragile bones

  • Hot flashes

  • Headaches

  • A dry vagina

  • Loss of sex drive

  • Loss of mental focus and multitasking skills?

  • For those who decide that these symptoms are unbearable, they often resort to synthetic pharmaceutical hormone replacement products. These synthetic hormones are the ones that the Women's Health Initiative (WHI) utilized, and were found to lead to increase cardiovascular and cancer risk.

  • Fortunately, Bio-equivalent hormone therapy (BHRT) offers a more alternative solution. They not only offer potential relief from menopausal symptoms, but they can also offer increased quality of life in several areas.
    Aging skin is often the result of declining estrogen levels. Collagen matrix formation is dependent on health estrogen levels. When estrogen levels decline, the collagen matrix suffers, and the result is seen in the face. The "falling face" or increased nasal-labial creases occur with age. Firm and supple skin is replaced with sagging dry skin, flattening of upper lips, loose sagging cheeks, and the infamous "turkey neck".

  • Why live with the changes while safe available therapies are available?

  • * Several methods of physiological BHRT exist. Creams, patches, drops, and gels are just some of the common ways to approach this therapy. I prescribe all the different forms, however, I prefer the SottoPelle ® Method.

  • Hormones that are supplemented in women:
    Estrogen, Testosterone, Progesterone

  • Please remember that the WHI Study determined that estrogen replacement therapy resulted in a slight increase in risk for breast and uterine cancer, as well as stroke.
    This study utilized conjugated estrogens and medroxyprogesterone. The hormones we utilize are bio equivalent estradiol and progesterone.

  • Testosterone Replacement in Women:
    Yes, in women. Women make testosterone also, albeit about 1/10th about as much as a man. But testosterone is important in women also, so correcting deficiency is important. During a woman's reproductive years, her ovaries not only make estrogen, but also testosterone. As she ages, or after she has had children, these levels decrease, even before menopause. Often the deficiency starts in their early thirties. Testosterone is important for sexual function, sexual response, and libido. Estrogen rules the brain, testosterone rules the body. A woman's body can't respond appropriately to sexual stimuli without testosterone. Additionally, testosterone helps maintain lean body mass, or muscle, as opposed to fat. It also has positive effects on those suffering from osteoporosis.

  • Other functions of Testosterone:

  • Prevents aches, pains and arthritis

  • Protects against cardiovascular disease

  • Protects against Alzheimer and dementia

  • Helps to stabilize blood sugar

  • Reduces breast cancer

  • Aids in the prevention of headaches/migraines